Dongyin guan lab. This score is (-26%) Below the National Average View Actual Score Our multidisciplinary research group focuses on nano-micro-macro scale materials and devices for biomedical applications 0 Works (2) sort Sort gov website The proposed site of research, University 1073/pnas mTOR plays a major role in cell growth, and dysregulation of this pathway has been frequently observed in human cancers 660 S Published on 10 Dec 2019 The hepatocyte clock and feeding control chronophysiology of multiple liver cell types View Background Details Are you Dongyin Guan? This is me - Control Profile? This is me - Control Profile Most frequent co-Author Wang, and X guowei@sas There are 3 professionals named "Dongyin Guan", who use LinkedIn to exchange information, ideas, and opportunities Office of Neuroscience Research from Case Western Reserve University Soft materials encompass the bulk of living tissues which possess characteristic living features such as being active, adaptive, and self-healing Yong Hoon Kim and other members of the Lazar lab for technical support and valuable discussions, particularly during the revision of this manuscript while sheltered in place Research 2022- Dongyin Guan [ The team found that as liver fat production increases, surprisingly What is single-cell ATAC-Se first_name}} Acting As {{delegateProfile Search Search In a new study published in Cell Stem Cell, a team of researchers from Perelman School of Medicine at the University of Pennsylvania, have demonstrated--using fat cells derived from human stem cells -- that individual genetic variation can be used to predict whether the TZD rosiglitazone will produce the unwanted side effect of increasing cholesterol levels in certain … Taiwan yesterday held live-fire drills in its northernmost territory, putting the spotlight on a remote island that is strategically located at a choke point near China — and potentially vulnerable to attack The Guan Lab is looking for talented individuals to join our team Rate Dongyin Duke Box 3711, DUMC Durham, NC 27710 basicInfo Toggle navigation A locked padlock) or https:// means you’ve safely connected to the RT @DrRGJonesLab: We are currently recruiting a Research Scientist in Proteomics to join the dynamic and diverse research team at @VAInstitute in Grand Rapids 1993-1998: State University of New York at Buffalo, USA Loop enables you to stay up-to-date with the latest discoveries and news, connect with researchers and form new collaborations Item Definition Through the innovative and comprehensive research strategy detailed in this proposal, the applicant, Dr program, USC Cell death & disease 5 (7), e1340-e1340 ONR@email Dr Postdoctoral training in zebrafish retinal developmental biology Zhou, L Fuyu Guan, Youwen You,Xiaoqing Li, Mary A edu; Research Areas Laminitis, Cell Biology, Protein Biochemistry, Theriogenology, Developmental Biology, Epithelial Stem Cells, Insulin Dysregulation, Proteomics FUYU GUAN Liver function is also influenced by nonhepatocytic cells, and the loss of hepatocyte REV-ERBs remodels the rhythmic transcriptomes and metabolomes of multiple cell types within the liver Yuxiang Zhang, 1, 2, 3 Bin Fang, 1, 2 Manashree Damle, 1, 2 Dongyin Guan, 1, 2 Zhenghui Li, 1, 2 Yong Hoon Kim, 1, 2 Maureen Gannon, 4 and Mitchell A A Kshirsagar, W Guan He received his B Current work in the Guan lab has been focused on elucidating how nutrient signals are detected by the cell to activate mTORC1 MSC 8111-04-09 KS Hsu, BJ Guan, X Cheng, D Guan, M Lam, M Hatzoglou, HY Kao 1172/JCI148278 Contributors Through creative molecular design and chemical Bioinformatics, University of Michigan, Ann Arbor By Dongyin Guan, Ying Xiong, Trang Trinh, Yang Xiao | Science Magazine LOW HIGH Lazar 1, 2 Keeping rhythm requires communicationIn mammals, daily cycles in physiology require the synchronized activity of circadian clocks in peripheral organs such as the liver, a hub of metabolism ] David Liu Translational control of PML contributes to TNFα-induced apoptosis of MCF7 breast cancer cells and decreased angiogenesis in HUVECs Research in the Guan lab is primarily focused on the TSC-mTOR and Hippo pathways Dongyin Guan is the Post-doct Researcher at The University of Pennsylvania in Philadelphia University of Pennsylvania; Perelman School of Medicine Nanopore back titration analysis of Loop is the open research network that increases the discoverability and impact of researchers and their work ( B) Relative expression of Rev-erb α and Rev-erb β in control and HepDKO livers from RPF mice Applied Filters Deacetylation of the tumor … Lazar Lab Reputation Score Range Trained as a molecular cell biologist in the 1980s, Dr Lazar 1 , 3 Bin Fang 1 , 2 , 3 , Dongyin Guan 1 , generated mice with hepatocytes that lack two transcriptional repressors known to be essential for clock function The understanding of these time signals, including gene expression, chromatin remodeling, epigenetics modification, translation control, and metabolites 0 Edited Publications Dongyin Guan 1 , Mitchell A The Guan lab explores the intra- and interorgan communications of time signals able to modulate the physiological function in metabolic disorders and cancer Dongyin Guan, Mitchell A He received his Ph ( A) Diagram of feeding schedule of ad lib feeding and RPF Dongyin Guan, 1, 2 Ying Xiong, 1, 2 Trang Minh Trinh, 1, 2 Yang Xiao, 1, 2 Wenxiang Hu, 1, 2 Chunjie Jiang, 1, 2 Pieterjan Dierickx, 1, 2 Cholsoon Jang, 3, 4 Joshua D 2019-2020 Biosensors and Bioelectronics 178, 113012, 2021 Home Dongyin Guan We are interested in moving biosensors out of the laboratory and into commercial applications, for example, to develop sensing techniques that could be employed in the analysis of environmental and biological samples, and for the application in field detection 42: 2021: A field-deployable mobile molecular diagnostic system for malaria at the point of need Soccio, Wenxiang Hu, Lindsey Peed, and Erika Briggs for their useful advice and technical assistance, and staffs in the Next-Generation Sequencing Core at University of Pennsylvania Perelman School of Medicine Dongyin Guan, Yong Hoon Kim, Raymond E Dongyin Guan, will gain extensive training in bioinformatics and metabolic physiology techniques, which are vital to a career in metabolic and circadian rhythm research at a top academic institution MS, Majored in Cell Biology Lazar, Perelman School of Medicine, University of Pennsylvania; <i>Cell</i> PHILADELPHIA - Mice fed a fattening diet develop new liver circadian rhythms that impact the way fat is accumulated and simultaneously burned, according to a new study published in Cell by researchers in the Perelman 2021-2022 none The Guan lab is highly collaborative and integrative of unbiased multiple-omics and loss-of-function tools to develop innovative chrono-pharmacological and chrono-nutritive therapeutic strategies relating to metabolic diseases and cancer Finally, alteration of food availability demonstrates the hierarchy of the cell-intrinsic hepatocyte clock mechanism and the feeding environment 215-898-0198 Directions Links of Interest Guan Robinson Identification of exvivo catabolites of peptides with doping potential in equine plasma by HILIC-HRMS Master student at the Guan Lab, University of Michigan In a new study published in Cell Stem Cell, a team of researchers from Perelman School of Medicine at the University of Pennsylvania, have demonstrated--using fat cells derived from human stem cells -- that individual genetic variation can be used to predict whether the TZD rosiglitazone will produce the unwanted side effect of increasing cholesterol levels in certain … Lab Galantino-Homer Laminitis Laboratory Mice fed a fattening diet develop new liver circadian rhythms that impact the way fat is accumulated and simultaneously burned Dongyin Guan Activities G Choi, D Song, S Shrestha, J Fax number 919-684-8885 D Guan, JH Lim, L Peng, Y Liu, M Lam, E Seto, HY Kao Wei Guo The islands are in the East China Sea off the coast of Fujian Province, China near the cities of Fuzhou … Welcome to the Yuanfang Guan Lab Michigan Medicine (link sends email) 215-898-9384 (office); 215-573-7255 (lab) Research Interests University of Pennsylvania, Institute for Diabetes, Obesity, and Metabolism, 12-102 Smilow Translational Research Center, 3400 Civic Center Blvd, Philadelphia, PA,19104 1998-2002: Harvard Medical School, USA Lazar; Proceedings of the National Academy of Sciences of the United States of America Guan D, Lim J, Peng L, Liu Y, Lam M, Seto E, Kao HY 93 /5 , Majored in Cell Biology Research Assistant at the Lana Garmire Lab, University of Michigan Xiaofeng Zhu has developed many statistical methods in the areas of association analysis, population stratification and admixture mapping, and has had extensive experience in the design and analysis of genetic studies over the past 20 years Dongyin Guan; Mitchell A Philadelphia, PA B expand_more Davies Lab was the first lab I worked for in UPenn and Ph Although HNF6 is known mainly as a transcriptional Join to connect 1 Dongyin Guan, PhD, Baylor College of Medicine, will discuss how environmental factors affect circadian misalignment and metabolic disease, including research from his lab looking at the relationship between metabolic health and the timing of eating and drug administration Research Assistant at the Guan Lab, University of Michigan Jason Sheltzer, BA, PhD, Recruitment to The University of Texas MD Anderson Cancer Center from Cold Spring Harbor Laboratory Collapse all M Skip slideshow Guan et al name}} lo g in; logo; Profiles; Workspace; Apps; Delegates; Back to My Account Fuyu Guan, Savannah Fay, Xiaoqing Li, Youwen You, Mary A Research Professor of Equine Forensic Chemistry; 610-436-3501 Credit: Annie Spikes, Dongyin Guan and Mitchell A 0 views XX downloads; XX citations; View All Publications We develop and deploy innovative materials, devices, and systems to enable next-generation medical diagnosis and life science research D student, Bioinformatics Photos Case Western Reserve University (4) Publication Date 1918894116 Share This Article: Copy Dongyin Township (Tungyin) (Chinese: 東引 鄉; pinyin: Dōngyǐn Xiāng; Wade–Giles: Tung 1-yin 3 Hsiang 1; Foochow Romanized: Dĕ̤ng-īng-hiŏng) is an insular rural township which is part of Lienchiang County (the Matsu Islands), Fujian Province, Republic of China (Taiwan) In a new study published in Cell Stem Cell, a team of researchers from Perelman School of Medicine at the University of Pennsylvania, have demonstrated--using fat cells derived from human stem cells -- that individual genetic variation can be used to predict whether the TZD rosiglitazone will produce the unwanted side effect of increasing cholesterol levels in certain … Credit: Annie Spikes, Dongyin Guan and Mitchell A Moreover, using gene-eRNA correlation, we detail the steps necessary to identify functional enhancers Dongyin Guan is currently a post-doctoral fellow and supported by F32 and K01 awards Drug Testing and Analysis Volume 12: 771-784, 2020 Class of 1965 Endowed Term Professor of Biology Find more info on AllPeople about Dongyin Guan and The University of Pennsylvania, as well as people who work for similar businesses nearby, colleagues for other branches, and more people with a similar name GRO-seq is particularly appealing for the study of circadian transcription, as it provides an unbiased and detailed map of functional genomic sites targeted by core clock TFs D 86 2 Biology, Sun Yat Sen University Search within Dongyin Guan's work ( C) Phase correlation of hepatic rhythmic transcripts between ad lib and RPF mice University of Texas Health Science Center, will discuss research 33 Dongyin Guan, PhD, Recruitment to Baylor College of Medicine from the University of Pennsylvania - $2,000,000; Joshua Riback, BA, PhD, Recruitment to Baylor College of Medicine from Princeton University - $2,000,000 Degree from Hangzhou University in Zhejiang China, and subsequently completed his Ph 4 Control of liver diurnal rhythms by the hepatocyte clock and feeding S By harnessing the unique physical, chemical, and biological properties in nano St Welcome, {{sessionUser Drawing inspiration from nature, the Guan Lab is focused on the design, synthesis, and study of dynamic soft materials and functional biomaterials 1989-1992: Institute of Botany, Chinese Academy of Sciences, China Yao Xiao ‪Pennsylvania State University‬ - ‪‪Cited by 2,642‬‬ - ‪Lab-on-a-Chip‬ - ‪Micro/nanofluidics‬ - ‪Point-of-Care Testing‬ Robinson A comprehensive approach to detecting multitudinous bioactive peptides in equine plasma and … Mice fed a fattening diet develop new liver circadian rhythms that impact the way fat is accumulated and simultaneously burned, according to a new study published in Cell by researchers in the wustl upenn Office Location 255 Nanaline Duke Market-leading rankings and editorial commentary - see the top law firms & lawyers for Corporate and M&A: PRC firms in China Cell：肝脏脂肪含量的增加 身体燃烧脂肪的能力也会上调 ，对于制定治疗肥胖相关疾病对策很有必要。 饮食引发的肥胖会重塑肝脏生物钟 “我们推测，饮食诱导的生物钟变化（反对脂肪代谢过程）是为了应对营养过剩，确保脂肪燃烧率超过脂肪累积率。”第一作者Dongyin Guan博士表示道。 A Biblioteca Virtual em Saúde é uma colecao de fontes de informacao científica e técnica em saúde organizada e armazenada em formato eletrônico nos países da Região Latino-Americana e do Caribe, acessíveis de forma universal na Internet de … Credit: Annie Spikes, Dongyin Guan and Mitchell A Dongyin Guan; Affiliations , 2014 Although the Ministry of National Defense says the exercises on Dongyin Island (東引), part of the Taiwan-controlled Matsu Islands off the coast of Fuzhou, … Lazar’s team, led by postdoctoral fellow Dongyin Guan, PhD, established a new mouse model that can specifically disrupt the internal clock in hepatocytes, the major cell type in the liver, which is a Distinguished Professor in the Department of Pharmacology and Moores Cancer Center at UCSD edu Kun-Liang Guan Han, S In a new study published in Cell Stem Cell, a team of researchers from Perelman School of Medicine at the University of Pennsylvania, have demonstrated--using fat cells derived from human stem cells -- that individual genetic variation can be used to predict whether the TZD rosiglitazone will produce the unwanted side effect of increasing cholesterol levels in certain … 2002-2003: University of Notre Dame, USA Here we show that deletion of HNF6 in livers of adult C57Bl/6 mice leads to hepatic steatosis in mice fed normal laboratory chow 2020 09 11; 369(6509):1388-1394 2 Edited Research Topics generated mice with hepatocytes that lack two transcriptional Share sensitive information only on official, secure websites Here we provide a detailed protocol, from wet lab procedures to bioinformatics analysis, for performing GRO-seq and mapping genome-wide active enhancers in mouse livers edu Journal of Clinical Investigation 2021-08-02 | Journal article DOI: 10 Although both the heat shock protein 70 (HSP70) and the activating transcription factor 5 (ATF5) have been shown to promote cell … Found 11010 colleagues at The University of Pennsylvania His laboratory has made seminal contributions in two areas of basic This is me - Control Profile data His post-doctoral work in Jack Dixon’s lab lead to multiple discoveries, including 2 Editorial Contributions 2020-2021 edu Map open chromatin and understand the machinery behind gene regulation in exquisite detail at the single-cell level with ATAC-Seq Louis, Missouri 63110-1010 Dongyin Guan's 12 research works with 285 citations and 2,034 reads, including: Isoform-specific functions of PPARγ in gene regulation and metabolism Guan D, Xiong Y, Trinh TM, Xiao Y, Hu W, Jiang C, Dierickx P, Jang C, Rabinowitz JD, Lazar MA Report this profile Experience Owner D at Purdue University with Henry Weiner Here, we describe a comprehensive protocol, ranging from wet lab to in silico analysis, for detecting and quantifying circadian transcription of genes and eRNAs Contact: gyuanfan@umich About the Lab Dongyin Guan Owner, 1 Mountain View, California, United States 20 connections Science Lazar Proceedings of the National Academy of Sciences Dec 2019, 116 (50) 24919-24921; DOI: 10 Euclid Ave Interconnections between circadian clocks and metabolism Guan has devoted his more than 3 decades of research career to understanding the fundamental mechanisms of cancer employing molecular and cell biological approaches combined with sophisticated mouse models of cancer This experimental manipulation unexpectedly disrupted rhythmic gene expression and metabolism not only in hepatocytes but also in other liver cell types 610-925-6246; hghomer@vet View the profiles of professionals named "Dongyin Guan" on LinkedIn Mechanisms of high fat diet-induced circadian hepatic transcription and lipid metabolism reprogramming Guan, Dongyin University of … Fig 2014 Y Dongyin Guan Mailing Address Department of Biochemistry Nanaline H